Immunoregulation of Inflammation
Immunoreceptors control innate and adaptative immunity which are essential for appropriate responses to infections and prevention of chronic inflammation or development of auto-immune diseases. Immunoglobulins are one of key molecules that acting through interaction with specific Fc receptors (FcR) can modulate immune responses. FcR intracellular signaling are central for either anti- or pro-inflammatory responses and are currently being exploited as targets for therapeutic approaches.
Renato Monteiro is professor of Immunology at Paris Diderot University and head of the Center for Research on Inflammation - INSERM U1149 & CNRS ERL8252 located at Bichat Hospital campus in Paris. After obtaining his medical degree in Brazil and then completing a residency in nephrology, he moved to Paris in 1982 to study nephrology at the Necker Hospital under the mentoring of Professor Jean Berger. Prof. Monteiro was awarded the 1986 Prize of the French Society of Nephrology for his work on IgA nephropathy, notably for the identification of abnormal IgA in Berger’s disease. He later studied immunology at the University of Birmingham in Alabama with Professor Max Cooper. Prof. Monteiro’s work in Prof. Cooper’s lab led to the identification of the IgA Fc receptor I (CD89). He defended his PhD thesis in immunology in 1993 at Paris Diderot University.